p53 mutations in squamous cell carcinomas from renal transplant recipients.

نویسندگان

  • M A Bennett
  • A O'Grady
  • E W Kay
  • M Leader
  • G M Murphy
چکیده

40 Meyn, R. E., Stephens, L. C., Voehringer, D. W., Story, M. D., Mirkovic, N. and Milas, L. (1993) Radiat. Res. 136, 327-334 Hallahan, D. E., Spriggs, D. R., Beckett, M. A,, Kufe, D. W. and Weichselbaum, R. R. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 10104-10107 Kaplan, E. B., Warner, B. K., Papes, R. A. and Wispe, J. R. (1994) Pediatric Res. 35, 84 Frank, L., Iqbal, J., Hass, M, and Massard, D. (1988) FASEB J. 2,490 Stein, B., Rahmsdorf, H. J., Steffen, A., Litfin, M. and Herrlich, P. (1989) Mol. Cell. Biol. 9, 5169-5181 41 Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. and Craig, R. W. (1991) Cancer Res.

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Mutations of p53 Gene in Skin Cancers: a Case Control Study

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Human skin carcinoma arising from kidney transplant-derived tumor cells.

Tumor cells with donor genotype have been identified in human skin cancer after allogeneic transplantation; however, the donor contribution to the malignant epithelium has not been established. Kidney transplant recipients have an increased risk of invasive skin squamous cell carcinoma (SCC), which is associated with accumulation of the tumor suppressor p53 and TP53 mutations. In 21 skin SCCs f...

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 25 1  شماره 

صفحات  -

تاریخ انتشار 1997